Case Study #1

15-Year-Old Male with Level 3 Autism

A 15-year-old boy diagnosed with Level 3 Autism, barely verbal, and experiencing severe behavioral challenges. He had frequent violent outbursts, often attacking peers and staff at school.

As a result, he was sent home 3 days a week, greatly impacting his education and social development.

Genomic Findings:

His functional genomic testing revealed:

• 12 gene variants impacting Vitamin D metabolism, transport, and receptor function (including VDR, GC, CYP2R1, CYP27B1).

• Significant inflammation markers.

• Heavy metal burden.

• Methylation inefficiencies (likely involving MTHFR, MTR, CBS, or related pathways).

Personalized Interventions:

Optimized Vitamin D:

• Targeted dosing based on gene SNPs and lab levels.

• Supported co-factors (magnesium, K2, A).

Reduced Inflammation:

• Added anti-inflammatory nutrition and antioxidants.

• Addressed gut and immune triggers.

Detoxified Heavy Metals:

• Safe binders and drainage pathways.

• Supported glutathione and GST pathways.

Nourished Methylation:

• Individualized B vitamin support.

• Managed homocysteine and transsulfuration flow.

Outcomes (4 months)

Behavior:

• Violent outbursts ceased completely.

• No longer sent home from school.

Cognition:

• Improved self-regulation.

• Advanced 3 grade levels in academic performance.

Communication:

• Began responding to questions consistently.

• Significantly more verbal, spontaneous speech increased.

Key Insights:

This case highlights how addressing foundational genomic imbalances —

especially Vitamin D regulation, inflammation, heavy metal detox, and methylation —

can dramatically improve behavior, learning, and communication in severe autism.