Cast Study #2

6-Year-Old Girl - Extreme Eczema, ADHD, OCD,

Level 2 Autism

A bright 6-year-old girl with Level 2 Autism presented with multiple complex challenges:

• Extreme eczema covering large areas of her skin.

• ADHD, high anxiety, and frequent tantrums.

• Obsessive-compulsive behaviors (OCD), rituals, and rigid routines.

• Very thin and underweight, despite good appetite.

• Exceptionally intelligent, but struggles with focus and emotional regulation.

Genomic Findings:

Her functional genomic testing uncovered key root causes:

• Digestive pathway dysfunction (e.g., DAO, FUT2, gut permeability genes) contributing to skin inflammation.

• Low glutathione capacity, due to GST and GPX variants, limiting detox.

• Elevated IL-6 and IL-13 pathways, indicating chronic systemic inflammation.

• Evidence of mercury and manganese burden, linked to oxidative stress and behavioral symptoms.

Personalized Interventions:

Addressed Digestive Issues:

• Gut-healing nutrition and targeted probiotics.

• Supported DAO/histamine breakdown as needed.

Balanced Glutathione:

• Supported synthesis and recycling (NAC, selenium, sulfur amino acids).

• Reduced oxidative stress.

Modulated IL-6 and IL-13:

• Added anti-inflammatory support: flavonoids, Omega-3s, low-histamine diet.

• Targeted herbs and nutrients to calm cytokine activity.

Detoxified Mercury & Manganese:

• Gentle chelation with safe binders.

• Optimized excretion pathways.

Outcomes:

Skin:

• Eczema cleared up completely — no more itching or lesions.

Behavior & Mental Health:

• OCD behaviors resolved, no more rigid rituals.

• Anxiety significantly improved; tantrums reduced.

Growth:

• Healthy weight gain for the first time in years.

• Improved nutrient absorption.

Overall:

• Brighter mood, better focus, and more resilience.

Key Insights:

This case shows how targeted functional genomics can reveal hidden connections between gut health, detox pathways (like glutathione), inflammatory cytokines (IL-6, IL-13), and behavioral conditions — empowering a personalized plan that resolved her skin condition and transformed her emotional and physical health.